Platelets found in the tumor microenvironment as a consequence of the creation of new blood vessels are activated and release a series of cytokines, growth factors, and factors, such as VEGF, CCL5, PDGF, TGFβ, PG, TPM3, LPA, PF4, PAF, and HGF, that promote EMT [15]. The gene discussed is VEGFA; the disease is neoplasm.