In our article, we focused only on selected ones—nesfatin-1, preptin, myonectin, omentin-1, gremlin-1, galectin-3, neuregulin-4, xenopsin-related peptide, xenin, neudesin, and lipocalin-2—and investigated their associations with insulin resistance in patients with PCOS. The gene discussed is NUCB2; the disease is polycystic ovary syndrome.