Saturated and monounsaturated fatty acids (SFAs and MUFAs) are part of de novo biosynthesis involving the enzyme complex fatty acid synthase (FASN) and delta-9-desaturase activity (∆9D, stearoyl-CoA desaturase, SCD-1); both of these enzymes are subject to overexpression in cancer [21]. The gene discussed is SCD; the disease is cancer.