In the post-inflammatory phase of colitis (Day 14), immunofluorescence analysis performed on the myenteric plexuses revealed a slight but significant decrease in PGP 9.5 (neuronal marker) immunoreactivity (p < 0.01) and a parallel up-regulation of GFAP (p < 0.05) in DNBS rats with respect to controls (vehicle; Figure 7A,B, respectively). This evidence concerns the gene GFAP and colitis.