A higher prevalence of APA and AHA was observed in ICI-treated patients compared to controls; in detail, after nine weeks of ICI treatment, 7 out of 13 patients became APA-positive, and three became AHA-positive, also showing an increase in prolactin and a decrease in ACTH and IGF-1 levels compared with basal values. Here, PRL is linked to autoimmune hemolytic anemia.