Moreover, exposure of S283A-PD-L1-MDA cells to PD-1 elevated tumor cell growth (Figure 5(A2b)), but only at 1.2 ± 0.7-fold induction, compared to 1.9 ± 0.5-fold induction in WT-PD-L1 cells (Figure 2(A3)), at day five after cell plating. The gene discussed is CD274; the disease is neoplasm.