NFKBIA and colorectal carcinoma: When comparing the baseline IκBα expression levels in CRC cell lines with different MS status, we observed that the mean IκBα level in MSS CRC cell lines was significantly higher compared to MSI CRC cell lines (MSS vs. MSI, 25.37 ± 2.40 μM vs. 14.91 ± 2.72 μM, p = 0.008) (Figure 9B).