Most recently, a single-center analysis of multiple genes involved in tumor inflammation and angiogenesis revealed CXCR1 (interleukine-8-receptor alpha—IL-8RA) +860 C>G heterozygous polymorphism to be an independent prognostic factor for DFS, cancer-specific survival and OS in patients with pCCA [65]. Here, CXCR1 is linked to neoplasm.