IL1B and Pancreatic cysts: Whilst IL-1B’s expression in pancreatic cyst fluid may be a prognostic marker, with a positive predictive value and negative predictive value of of 71% and 75%, respectively, along with a sensitivity and specificity of 79% and 95%, respectively; the exact role of IL-1B in promoting or inhibiting histological progression and interaction with bacteria in PDAC remains to be determined [171].