MBL (mannose binding lectin) recognises fungal pathogens and binds fungal wall glycans in order to activate the lectin pathway of the complement cascade, triggering C3 convertase which cleaves C3, releasing subunit C3a, which interacts with C3a receptors found on tumour cells and, in doing so, promote tumour growth [56,57,58]. The gene discussed is C3; the disease is neoplasm.