TRIB1 and systemic lupus erythematosus: Under physiological conditions, Trib1 overexpression led to a decreased serum immunoglobulin (Ig)G1 level, while a decrease in anti-double stranded DNA (anti-dsDNA) IgM production was observed in a model of SLE induced by an injection of lipopolysaccharide (LPS) from Salmonella typhimurium.