TNFAIP3 and MALT lymphoma: In a small series of four pSS patients with cryoglobulinemia but without MALT lymphoma, pathogenic mutations in small fractions of circulating B-cells were observed in genes that are often associated with common B-cell lymphomas, such as CARD11, TNFAIP3, CCND3, ID3, BTG2 and KLHL6 [4].