TP53 and eccrine porocarcinoma: Recently, Denisova et al. performed the analysis of WES (whole-exome sequencing) data that revealed that TP53 (tumor protein p53), FAT2 (FAT atypical cadherin 2), KMT2D (lysine methyltransferase 2D), and CACNA1S (calcium voltage-gated channel subunit alpha1 S) were the most frequently mutated genes among 14 cases of eccrine porocarcinomas [44].