CD274 and neoplasm: In contrast to this mechanism of action yet in line with previous results [15,17,22], we found VISTA expression on sarcoma cells to be associated with the expression of CD3 (univariate and in a logistic regression model) as well as the presence of TILs and the expression of PD-1 and PD-L1 (univariate), suggesting that VISTA may play a role in the inflamed tumour microenvironment.