This summary demonstrated lifetime risk was 5–7% for MLH1 carriers, 0.2–9% for MSH2 and EPCAM carriers, and <1–7.9% in MSH6 carriers, and importantly notes that the risk for PMS2 carriers is unknown, illustrating the uncertainty of whether gastric cancer risk is increased for PMS2 carriers. The gene discussed is MSH2; the disease is gastric cancer.