Indeed, an inverse relationship between BRCA1 and the EMT marker Vimentin as well as cytoskeletal proteins typical of basal-like tumors, i.e., CK5/6, CK14, CK17, were observed in BC, and underscore the central role of BRCA1 in suppressing invasiveness and metastasis [91]. The gene discussed is BRCA1; the disease is breast cancer.