The intratumoural injection of a HSV-2 OV resulted in the upregulation of a range of chemokines, including crucial T cell attractant CXCR3 ligands CXCL9 and CXCL10, as well as CCL2, CCL3, and CCL4, increasing the migration of adoptively transferred T cells to tumours in a model of pancreatic adenocarcinoma [94]. This evidence concerns the gene CCL2 and neoplasm.