The expression of CXCR2 in primary T cells enhanced migration toward both recombinant and melanoma-tumour-derived CXCL1 in vitro, and the surface expression of CXCR2 enhanced the accumulation of T cells in tumours in a mouse model of melanoma, improving tumour regression and survival [55,56]. The gene discussed is CXCL1; the disease is neoplasm.