SMAD3 and urinary bladder carcinoma: Certain miRNAs have been reported to target and reduce SMAD3 expression, thereby inhibiting the EMT process in bladder cancer cells, including the miR-665–SMAD3 axis [60], miRNA-145–TGFBR2–SMAD3 axis [50], and miR-323a-3p–MET–SMAD3 axis [61], and only one ceRNA profiling was employed to identify the PlncRNA-1–miR-136–SMAD3 axis [62].