Non-tumor-bearing mice showed an increase in both circulating and tissue-infiltrating neutrophils after TFR (Figure S5A–C), consistent with the upregulated expression of the neutrophil chemoattractant ligands CXCL2 and CXCL5, overexpression of the surface receptor CD36 that is implicated in several aspects that are related to fatty acid metabolism, and the downregulated gene expression of the regulator of lipid biosynthesis and adipogenesis sterol regulatory element-binding protein 1 (SREPB1c), and fatty acid synthase (FAS) in the livers of fasted mice (Figure S5D). The gene discussed is CXCL2; the disease is neoplasm.