PIK3CA and ovarian carcinoma: In conjunction, we observed that endometroid ovarian cancer cell line MCW-OV-SL-3 cells as well as A2780 exhibited increased phosphorylation of AKT both at T308 and S473 residues, phosphorylation of p85 subunit of PI3K, and phosphorylation of ERK1/2 compared to normal MCW-OSE-1 cells (Figure 1I).