CD44 and cancer: We next determined the levels of EMT markers (E-Cadherin, N-Cadherin) and cancer stemness-related markers (c-Kit, CD44, and prominin) in both cell lines and found that the cisplatin-resistant derivative of cell lines expressed high levels of N-Cadherin and low levels of E-Cadherin as well as c-Kit, CD44, and prominin proteins (Figure 4E).