VEGFA and Insulin resistance: Other RTKs are influenced by membrane gangliosides as well, illustrated by several examples such as GM3-mediated inhibition of FGFR activation and cell proliferation [211], reduction in vascular endothelial growth factor (VEGF)-induced angiogenesis [212], attenuated signaling of insulin receptors contributing to insulin resistance [213], GM1-induced, reduced PDGFR signaling [214], and facilitation of nerve growth factor-stimulated TrkA receptor activation eliciting neurotrophic actions [215].