A further literature review identified nine genes implicated in promoting drug resistance in MM cells, including CDK6 [58], HIF1A [59], MCL1 [60], MITF [61], PPP3CA [62], PTP4A3 [63], RUNX3 [64], SGK1 [27,65], and USP14 [66] (Supplementary Table S4). Here, CDK6 is linked to Miyoshi myopathy.