EP300 and non-small cell lung carcinoma: Since we found that EP300 is more abundant on chromatin in NSCLC cells after long-term exposure to cisplatin, and, particularly, at the ABCC10 promoter that allows for relatively strong overexpression of this gene in cisplatin-resistant phenotype, we decided to test the direct ABCC10 response to a single dose of cisplatin (10 μM).