For example, TRPV1 is under-expressed in glioblastoma multiforme but over-expressed in lung adenocarcinoma; CNR1 (gene coding for CB1 receptors) is under-expressed in lung adenocarcinoma, thyroid carcinoma, breast invasive carcinoma, and uterine corpus endometrial carcinoma and over-expressed in cholangiocarcinoma; CB2 receptors are overexpressed in HR+ breast cancer and gliomas [5,87,88]. Here, CNR1 is linked to lung adenocarcinoma.