To elucidate the underlying mechanism of oncogenic Derlin-1 in promoting migration and invasion of UTUC, we used TargetScan 7.2 software (http://www.targetscan.org/vert_72/, accessed on 15 March 2018) to explore the possible upstream miRNA regulators of Derlin-1 [32]. This evidence concerns the gene DERL1 and renal pelvis/ureter urothelial carcinoma.