ALB and cancer: Of note, when the same experiment was performed in non-malignant breast epithelial MCF10A cells, no significant differences were observed in Pba uptake between MAL-PTX2S@Pba and BOC-PTX2S@Pba NPs (Figure S10), thus confirming, at least in vitro, the capability of HSA-binding nanocarriers to increase drug selective internalization exclusively in cancer cells.