We found that highly expressed HPRT1 was also associated with poor prognosis and the OS of kidney renal papillary cell carcinoma (KIRP) (p = 0.00026), brain lower grade glioma (LGG) (p = 0.031), liver hepatocellular carcinoma (LIHC) (p = 0.017), uterine carcinosarcoma (UCS) (p = 0.0091), lung adenocarcinoma (LUAD) (p = 0.023), lung squamous cell carcinoma (LUSC) (p = 0.023), mesothelioma (MESO) (p = 3.3 × 10−6) within the TCGA project (Figure 7B). Here, HPRT1 is linked to squamous cell lung carcinoma.