NKX3-1 and posterior cortical atrophy: The m6A reader YTHDF2 has been found upregulated in PCa, its expression predicts worse overall survival, and its knockdown inhibits proliferation and migration of PCa in vivo and in vitro, by binding and degrading m6A-methylated LHPP and NKX3-1 mRNAs, resulting in increased AKT activity [159].