In this study, silencing of either MBNL1 or CELF1 in the control and DM1 cultured myotubes did not affect the abundance of circZNF609, circRTN4, and circRTN4_03 and the authors explained this finding by the possible role of other splicing regulatory factors, or higher stability of circRNAs compared to their linear counterparts [80]. Here, MBNL1 is linked to myotonic dystrophy type 1.