Among these 12 lncRNAs constructing the prognostic signature, LINC02408, AL589765.4, AL121790.2, YTHDF3-AS1, LINC00460, and CYTOR functioned as risk factors for the prognosis of BC patients, while AC068473.4, USP30-AS1, U73166.1, LINC00987, CD2BP2-DT, and LINC01016 acted as protective factors. The gene discussed is YTHDF3; the disease is breast cancer.