Interestingly, the GO term “alcoholism” was enriched in genes associated with the “CGI-free intergenic UMR” category, including Shc3, Shc4, Araf, Fosb, Hdac11, Adcy5, Creb3l2, Gnai2, Grin2d, and Ppp1r1b. This evidence concerns the gene ADCY5 and alcohol drinking.