IL10 and Insulin resistance: In 3T3-L1 IR cells, similar to the SAT-derived IR adipocytes, we observed approximately a 4.5-fold increase of the IL10 expression level in IR cells, compared to control cells after 48 h after induction insulin resistance (p = 0.014), and more than a twofold increase after 72 h (p = 0.001) (Figure 2A).