IL6 and alkaline phosphatase measurement: Additionally, increased IL-6 and hs-CRP concentrations in the group of smoking AP patients with the GC (p < 0.0001, p = 0.0294), CC (p < 0.0001, p = 0.0227), and GG (p = 0.0282, p = 0.0019) genotypes for rs1800795 in the IL6 gene compared to smoking healthy subjects were found (Table 3).