While cross checking our results with TCGA, we found that the virus infection-relation pathways were significantly enriched with many pathogenic genetic variations, which is consistent to some extent with the result in TCGA showing that the driver genes of cervical cancer in the TCGA-CESC dataset were mainly enriched in the KEGG pathway, including human T-cell leukemia virus 1 infection, human papillomavirus infection, viral carcinogenesis, human cytomegalovirus infection and PI3K-Akt signaling pathway. Here, AKT1 is linked to viral infectious disease.