From the PANTHER analysis results, the differentially expressed proteins in each group focus on p38 MAPK pathway, p53 signaling pathway, PI3K-Akt signaling pathway, Huntington’s disease, ubiquitin proteasome pathway, TGF-beta signaling pathway, wnt signaling pathway, hedgehog signaling pathway, integrin signaling pathway, apoptosis signaling pathway, etc. Most of them were related to a wide spectrum of cellular functions, such as proliferation, apoptosis, differentiation and migration. This evidence concerns the gene TP53 and Huntington disease.