Analyses of alleles and genotypes crude frequencies of nine SNPs of genes codifying for key cytokine and receptors involved in kidney damage pathogenesis do not allow to identify associations with the Klotho, in spite of the above-mentioned data on the role of rs577912 polymorphism as risk factors of mortality in dialyzed patients [13] and the role of rs9536314 in the so-called longevity trait [17]. Here, KL is linked to Nephropathy.