Typing of MIF rs1007888, which was found associated with an increased risk of diabetes [48], does not indicate a role for this SNP in ESRD predisposition, whereas the C positive genotypes of rs755622, located at −173bp before the transcription initiation site of MIF gene and associated with a higher production of the cytokine [73], is more frequent in patients than in controls. This evidence concerns the gene MIF and diabetes mellitus.