E2F2 and Familial prostate cancer: In addition, we encountered 11 DE genes belonging to the KEGG Senescence pathway (CCNB1, CCNB2, FOXM1, CCNA2, CDK1, CCNE2, CDC25A, E2F2, CDKN2A, MAPK13, RBL1) and 6 DE genes from the Prostate Cancer Pathway (PDGFRB, PDGFRA, CCNE2, E2F2, EGFR, ZEB1), with CCNE2 and E2F2 belonging to both.