Scharf, J. M., et al. conducted a meta-GWAS analysis of Tourette’s syndrome (TS) and found that the rs10277969 in CNTNAP2 was an important candidate SNP (P = 7.8 × 10−4) [54], and CNTNAP2 variants were associated with complex disorders such as depression, schizophrenia, and dyslexia [55]. This evidence concerns the gene CNTNAP2 and depressive symptom measurement.