As expected, basal glycemia, insulin, HbA1c (glycated hemoglobin), and markers of oxidative stress (nitrotyrosine and 8-iso-PGF2a (8-iso prostaglandin F2a)) were increased in diabetes, and FMD (flow-mediated vasodilation; a marker of endothelial function) was decreased. The gene discussed is INS; the disease is diabetes mellitus.