The pathway with the smallest p value among these pathways is the CVD–hematological disease pathway, which involved 15 proteins, namely MYOCD, PROS1, C2, SERPINA10, CRP, F5, C5, CFB, FGG, CFH, F12, PRDX2, PROZ, PPIA, and HABP2 (Figure 2). The gene discussed is PROS1; the disease is hematologic disorder.