Turrell et al. found that expression of Bbc3, Ccng1, and Cdkn1a were impacted by presence of the Trp53 R270H mutant in their lung cancer GEM [71], and Wijnhoven et al. showed that Bbc3 expression is impacted in their breast cancer GEM [70]. The gene discussed is CDKN1A; the disease is breast cancer.