We found no significant differences between the three groups in terms of TLR2 rs3804099, TLR2 rs3804100, and NLRP3 rs10754558 gene polymorphisms (p = 0.1339, p = 0.5971, and p = 0.5570), family history (p = 0.7700), gastroesophageal reflux (p = 0.2944), and biliary reflux (p = 0.4151). Here, NLRP3 is linked to gastroesophageal reflux disease.