HAVCR1 and Familial prostate cancer: To achieve this, as well as to investigate the localisation of HAVCR-1 in prostate tissue, total HAVcR-1 in prostate cancer (n = 2) and background control (n = 2) tissue samples were stained via IHC, Figure 1C. This revealed that the HAVcR-1 protein was expressed in prostate glandular epithelia.