CD4 and acute myeloid leukemia: To further investigate the role of TNT in HIV/HIV-C infection, DCs, alone or in co-culture with CD4+ T cells, were treated with cytarabine (AraC), which is a pyrimidine nucleoside analog recently demonstrated to reduce TNT formation by interfering with NFκB activation in acute myeloid leukemia (AML) [53] and in HTLV-1 cells [62].