At day 7 of hospitalization, after adjusting by age and sex, we found that only [TIMP-2] × [IGFBP7] ≥ 0.2 (ng/mL)2/1000 remained associated with risk for AKI (HR = 5.91, 95% CI: 1.06–32.7; p = 0.042). The gene discussed is TIMP2; the disease is acute kidney injury.