After adjusting for possible confounding variables, the multivariate analysis indicated that the risk factors for AKI during the hospitalization period were male gender (HR = 7.57, 95% CI: 1.28–44.8; p = 0.026) and [TIMP-2] × [IGFBP7] ≥ 0.2 (ng/mL)2/1000 (HR = 7.23, 95% CI: 0.99–52.4; p = 0.050) (Table 3). The gene discussed is TIMP2; the disease is acute kidney injury.