Cellular processes, such as cell adhesion, polarity, and survival, and metabolism pathways, such as ERK/MAPK (“MAPK cascade”, “MAP kinase activation”), PI3K/AKT (“phosphatidylinositol 3-kinase signaling”, “regulation of phosphatidylinositol 3-kinase signaling”) and mTOR (“MTOR signaling”), appear to be able to regulate, through their functionality, the memory processes in AD. Here, PIK3CA is linked to Alzheimer disease.