MAPT and Alzheimer disease: Table 2 reports the main CSF parameters in the study groups. In the AD group, the mean Abeta 1–42 concentration was 613.93 pg/mL. According to a recent report [39], a concentration of Abeta 1–42 < 803 pg/mL does not contrast with the diagnosis of AD. The mean total and phosphorylated tau concentrations were, respectively, 580.27 and 69.93 pg/mL. According to Babapour and colleagues, a total tau concentration >374 pg/mL could be considered suggestive of neurodegeneration [39].