Over-expression of the β4GalNAcT3 gene in HCT116 colon cancer cells induced the production of the LacdiNAc group on N-glycans of β1-integrin and resulted in the promotion of migratory and invasive activities of the cells, and of the adhesive activities of the cells toward fibronectin, collagen-type IV, and laminin, respectively [45]. The gene discussed is B4GALNT3; the disease is malignant colon neoplasm.