Our preliminary data showed that galectin-3 binds to the LacdiNAc group in the β4GalNAcT4 gene-transfected breast cancer cells (unpublished data), indicating that the possible interaction of galectin-3 with the LacdiNAc group on N-glycans of integrins may play a role in the regulation of cell-to-substratum interaction, thus contributing to the induction of the MET. Here, LGALS3 is linked to breast cancer.