TRPM8 and prostate carcinoma: As in humans [15,16], the mouse prostate expresses a higher amount of Trpm8 than other murine tissues (Figure 1A), comparable to the levels of the channel found in normal prostate immortalized (RWPE-1 and PWR-1E) and prostate cancer human-cell lines (LNCaP, VCaP, C4-2) (Figure 1B).