S100A10 and cancer: The same study found that S100A10 protein expression was upregulated in human pancreatic tumours relative to adjacent non-ductal stroma and normal ducts (n = 89), and a genomic analysis of the relative expression levels of S100A10 across 33 different cancer types by the National Cancer Institute (NCI) revealed that S100A10 mRNA expression was the third highest in PDAC (n = 179) [181].