The plasminogen receptors ENO1, histone H2B, Plg-RKT, ANXA2 and S100A10 have been shown to be expressed at the cell surface of human monocytes/macrophages, where they are involved in plasminogen activation and play an important role in the recruitment and migration of macrophages to tumour sites [207,208,209,210]. This evidence concerns the gene ENO1 and neoplasm.