Moreover, the enhanced level of Ang-2 and sTie-2 was concomitant with the expression of sICAM-1 which was significantly higher in young Beninese patients with CM or SNCM as well as in children with coma and those who died (Figure 1, Figure 2 and Figure 3) C–E. This evidence concerns the gene ANGPT2 and type 2 diabetes mellitus.